ABSTRACT Of the approximately 10 million cases of Mycobacterium tuberculosis (Mtb) infections each year, over 10% are resistant to the frontline antibiotic isoniazid (INH).INH resistance is predominantly caused by mutations that decrease the activity of the bacterial enzyme KatG, which mediates the conversion of the pro-drug INH to its active form
Aeromonas hydrophila is a ubiquitous bacterium with various hosts that causes mass mortality in farm-raised fish species and significant economic losses.The current antibiotic treatment is ineffective in controlling this bacterium infection in aquaculture species.Therefore, an evaluation of potential phytobiotics is needed to find an alternative an
Abstract In this paper, we analyze the clustering of galaxies using a modified theory of gravity, in which the field content of general relativity has been be increased.This increasing in the field content of general relativity changes the large distance behavior of the theory, and in weak field approximation, nemacor maxx it will also modify the l
BackgroundMounting evidence suggests that increased gut permeability, or leaky gut, and the resulting translocation of pathobionts or their metabolites contributes to the pathogenesis of Systemic Lupus Erythematosus.However, the mechanisms underlying the induction of gut leakage remain unclear.In this study, we examined the effect of a treatment wi